Juvenile versus adult-onset ankylosing spondylitis: are we comparing apples and oranges?
نویسندگان
چکیده
منابع مشابه
PReS-FINAL-2168: Comparison of safety and retention rate of TNF antagonist therapy in juvenile-onset and adult-onset ankylosing spondylitis: data from the spanish registry biobadaser 2.0
Introduction Ankylosing spondylitis (AS) is a chronic inflammatory disease that belongs to the group of spondyloarthritis, which involves the spine, peripheral joints and entheses. Juvenile-onset AS affects children under the age of 16 years and present a clinical course different from adultonset AS. Several randomized clinical trials have shown that TNF antagonists are an effective alternative...
متن کاملComparison in clinical features and life impact between juvenile-onset and adult-onset ankylosing spondylitis.
BACKGROUND/AIM To compare the differences in clinical characteristics and disease impact on life between patients with juvenile-onset ankylosing spondylitis (JoAS) and patients with adult-onset AS (AoAS). MATERIALS AND METHODS Demographic and clinical data were collected from 139 AS patients. Disease activity was defined with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Fu...
متن کاملPReS-FINAL-2115: Differences in musculoskeletal clinical expression between Spanish and Mexican patients with juvenile spondyloarthritis: data from the Mexespa project
Introduction Juvenile spondyloarthritis (J-spa) is characterized by a predominantly peripheral involvement and more frequent presentation as undifferentiated forms. However, like its adult-onset equivalent, it has the potential to develop structural damage and evolve to juvenile ankylosing spondylitis (J-AS), with consequent functional impairment that will last for the lifetime of the patient. ...
متن کاملAnkylosing spondylitis in North India: a clinical and immunogenetic study.
Fifty-one North Indian patients with ankylosing spondylitis (AS) are described with mean age of onset 21.2 years and male to female ratio of 16:1. AS began with peripheral arthritis in 47%, low back pain in 41%, acute anterior uveitis in 10%, and heel pain in 2% of the patients. 76% of 51 patients had one of the extra-axial features of AS: peripheral arthritis (61%), heel pain (24%), anterior u...
متن کاملTNF-alpha antagonists for treatment of juvenile ankylosing spondylitis
Background Juvenile onset sondylarthropathy is a term that refers to a group of human leucocyte antigen (HLA) -B27 associated inflammatory disorders affecting children under the age of 16 years. The increased expression of tumor necrosis factor alpha (TNF-alpha) in synovial tissue of patients with juvenile onset and adults with active ankylosing spondylitis suggests a significant pathogenic rol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of rheumatology
دوره 39 5 شماره
صفحات -
تاریخ انتشار 2012